Mindfulness is relaxing with present moment awareness. Mindfulness is a science developed around 3,500 years back. Mindfulness was popular before Buddha, but Buddha formalized it and popularized it among common people. In modern Western society, mindfulness has been adapted for use in treatment of stress and depression, especially preventing dementia and alzheimer’s and also for assisting with emotional regulation. The seven factors of mindfulness are discussed. There are about 200 scientific articles on the effectiveness of mindfulness meditation. Scientist observed that mindfulness practice reduces stress and decreases volume of grey matter in the amygdala.